Journal of Medical Physics
ORIGINAL ARTICLE
Year
: 2021  |  Volume : 46  |  Issue : 1  |  Page : 16--25

Dosimetric comparison of robotic and linear accelerator multi-leaf collimator-based stereotactic radiosurgery for arteriovenous malformation


Venkatesan Kaliyaperumal, Susan Abraham, Maragatha Veni, Susovan Banerjee, S Tamilselvan, Deepak Gupta, K Dayanithi, D Manigandan, Saumyaranjan Mishra, Shyam Singh Bisht, Tejinder Kataria 
 Division of Radiation Oncology, Medanta Cancer Institute, Medanta The Medicity, Gurgaon, Haryana, India

Correspondence Address:
Venkatesan Kaliyaperumal
Division of Radiation Oncology, Medanta Cancer Institute, Medanta The Medicity, Gurgaon, Haryana
India

Purpose: To investigate the dosimetric comparison of different collimators which are used in robotic radiosurgery (cyberknife-CK) and linear accelerator (LINAC) for stereotactic radiosurgery (SRS) in arteriovenous malformation (AVM). Materials and Methods: Twenty-five AVM patients were planned in CK using FIXED cone, IRIS collimator, and multi-leaf collimator (MLC) based in LINAC. Dosimetric comparison was performed using Paddick conformity index (CIPaddick) and International Commission on Radiation Units and measurements (ICRU) homogeneity index (HIICRU), gradient score (GS), normal brain dose received by 10cc (D10cc) and critical structure (brain stem, optic chiasma, optic nerves) doses. Paired sample t-test was used for statistical analysis. Results: Mean treatment volume was 3.16cc (standard deviation ± 4.91cc). No significant deviation (P =0.45, 0.237 for FIXED vs. IRIS and FIXED vs. MLC, respectively) was found in target coverage. For CIPaddick, the mean difference (MD) between FIXED- and MLC-based plans was 0.16(P = 0.001); For HIICRU, difference between FIXED and IRIS was insignificant (0.5, P = 0.823); but, when FIXED versus MLC, the deviation was 7.99% (P = 0.002). In FIXED- and MLC-based plans, significant difference was found in GS70 and GS40 (P < 0.041 and 0.005, respectively). MD between FIXED- and MLC-based plans for normal brain for 5Gy, 10Gy, 12Gy, and 20Gy were 36.08cc (P = 0.009), 7.12cc (P = 0.000), 5.84cc (P = 0.000) and 1.56cc (P = 0.000), respectively. AVM volume <0.7cc should be treated with CK FIXED and >0.7cc were treated by using FIXED or IRIS collimators. AVM volume > 1.4cc can be treated by either LINAC MLC-based SRS or CK. Conclusion: Our study shows CK collimator (IRIS and FIXED) could be able to treat brain AVMs in any size. Linac MLC-based SRS has some limitations in terms of conformity and low-dose spillage, and advantages like reduced treatment time and MU.


How to cite this article:
Kaliyaperumal V, Abraham S, Veni M, Banerjee S, Tamilselvan S, Gupta D, Dayanithi K, Manigandan D, Mishra S, Bisht SS, Kataria T. Dosimetric comparison of robotic and linear accelerator multi-leaf collimator-based stereotactic radiosurgery for arteriovenous malformation.J Med Phys 2021;46:16-25


How to cite this URL:
Kaliyaperumal V, Abraham S, Veni M, Banerjee S, Tamilselvan S, Gupta D, Dayanithi K, Manigandan D, Mishra S, Bisht SS, Kataria T. Dosimetric comparison of robotic and linear accelerator multi-leaf collimator-based stereotactic radiosurgery for arteriovenous malformation. J Med Phys [serial online] 2021 [cited 2021 Jun 19 ];46:16-25
Available from: https://www.jmp.org.in/article.asp?issn=0971-6203;year=2021;volume=46;issue=1;spage=16;epage=25;aulast=Kaliyaperumal;type=0