Journal of Medical Physics
ORIGINAL ARTICLE
Year
: 2013  |  Volume : 38  |  Issue : 2  |  Page : 67--73

A quantitative analysis of intensity-modulated radiation therapy plans and comparison of homogeneity indices for the treatment of gynecological cancers


Pushpraj Pathak, Sanjeev Vashisht 
 Department of Medical Physics, Jawaharlal Nehru Cancer Hospital and Research Centre, Bhopal, Madhya Pradesh, India

Correspondence Address:
Pushpraj Pathak
Jawaharlal Nehru Cancer Hospital and Research Centre, Idgah Hills, Bhopal, Madhya Pradesh
India

The aim of present study was to evaluate the intensity-modulated radiation therapy (IMRT) plans using different homogeneity and conformity indices in gynecological cancers, as well as to compare and find out the most reliable and accurate measure of the dose homogeneity among the available indices. In this study, a cohort of 12 patients were registered for evaluation, those receiving dynamic IMRT treatment on Clinac-2300C/D linear accelerator with 15-Mega Voltage (MV) photon beam. Dynamic IMRT plans were created on Eclipse treatment planning system with Helios dose volume optimization software. Homogeneity indices (HI) such as H index, modified H index, HI index, modified HI index, and S-index (sigma-index) proposed by M Yoon et al. (2007) were calculated and compared. The values of S-index vary from 1.63 to 2.99. The results indicate that the H and HI indices and their modified versions may not provide the correct dose homogeneity information, but the S-index provides accurate information about the dose homogeneity in the Planning Target Volume (PTV). Each plan was compared with 6-MV photon energy on the basis of S-index and conformity index (CI). Organs at risk (OAR) doses with 6-MV and 15-MV beams were also reported.


How to cite this article:
Pathak P, Vashisht S. A quantitative analysis of intensity-modulated radiation therapy plans and comparison of homogeneity indices for the treatment of gynecological cancers.J Med Phys 2013;38:67-73


How to cite this URL:
Pathak P, Vashisht S. A quantitative analysis of intensity-modulated radiation therapy plans and comparison of homogeneity indices for the treatment of gynecological cancers. J Med Phys [serial online] 2013 [cited 2021 Sep 24 ];38:67-73
Available from: https://www.jmp.org.in/article.asp?issn=0971-6203;year=2013;volume=38;issue=2;spage=67;epage=73;aulast=Pathak;type=0