Journal of Medical Physics

Year
: 1992  |  Volume : 17  |  Issue : 2  |  Page : 10--12

Extrapolated Response Dose (ERD) AS A Potential Guide In The Management Of Carcinoma Of Uterine Cervix


Sanjay S Supe1, Kumara Swamy2, Udaya M Kumar3, N Viswanathan4, N Anantha5 
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Correspondence Address:
Sanjay S Supe


A retrospective analysis of 291 patients with cancer of the uterine cervix treated with a combination of external and intracavitary radiotherapy was carried out. Patients were treated with external radiotherapy dose of 45 Gy in 20 fractions, 5 fractions per week or 42 Gy in 14 fractions, 3 fractions per week. For brachytherapy the total dose was 24 to 32 Gy at a dose rate of«SQ»1. 4 to 2.2 gy per hour. Treatment results in terms of response, survival, recurrence and complication were correlated with total Extrapolated Response Dose (ERD) values for point A (ERDTA) and for rectum (ERDT,). ERDTA values did not correlate with response, recurrence and survival rates (p value >0.05). ERDTA values correlated well with rectal complication rate (p value >0.025). Lack of correlation was observed between ERDT, with rectal complication rate (p value >0.1). In order to limit Grade II and Ill rectal complications to acceptable level, in combined external and intracavitary treatments, ERDTA value of less than 93 is suggested.


How to cite this article:
Supe S, Swamy K, Kumar U, Viswanathan N, Anantha N. Extrapolated Response Dose (ERD) AS A Potential Guide In The Management Of Carcinoma Of Uterine Cervix.J Med Phys 1992;17:10-12


How to cite this URL:
Supe S, Swamy K, Kumar U, Viswanathan N, Anantha N. Extrapolated Response Dose (ERD) AS A Potential Guide In The Management Of Carcinoma Of Uterine Cervix. J Med Phys [serial online] 1992 [cited 2021 Mar 2 ];17:10-12
Available from: https://www.jmp.org.in/article.asp?issn=0971-6203;year=1992;volume=17;issue=2;spage=10;epage=12;aulast=Supe;type=0