Journal of Medical Physics
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Year : 2004  |  Volume : 29  |  Issue : 2  |  Page : 77-79

"Internal Radiation Absorbed Dose Estimation In Human Brain Due To Techenetium-99m And Iodine-131"



Correspondence Address:
Moshrakul Alam


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Internal dosimetry is a branch of medical physics that deals with the measurement of the internally absorbed dose by an organ after applying isotopes. In this study, internal radiation absorbed dose has been calculated for 99mTc and 131I, which are frequently used for functioning tests and therapeutic treatments of thyroid, respectively. In these cases, some amount of isotopes are accumulated in other tissues like brain, which are very soft and cannot be regenerated if they are damaged. Using ionizing radiation inside the body and to ensure the safety of brain, the internal radiation absorbed dose has been calculated applying direct counting measurement. Accumulation of isotopes to target organ has been measured and this target organ is considered as primary target organ; also this organ is considered as source with respect to other organs. These organ counts have been measured by computer-based scintillation system. The amount of exposure in brain has been measured with the help of the data obtained from the special set-up equipment, including Nal detector, radiation survey meter and water phantoms of various sizes. Absorbed dose in brain for each isotope has been calculated by applying time-activity curve analysis. Finally, these results have been compared with the data in ICRP Reports 53 and 71.


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