Journal of Medical Physics
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Year : 1991  |  Volume : 16  |  Issue : 4  |  Page : 27-29

Effects Of Carbonterachloride And Liv-52 On The Clearance Rate Of 131I-Rose Bengal In Rat Liver

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D Dhawan

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131I-Rose bengal clearance test has been immensely used for the clinical assessment of functional hepatic abnormalities. It has been observed that external collimated scintillation probe employing 131I-Rose bengal is a rapid and less erroneous way of assessing polygonal cell function in liver. The present study demonstrates the protection of liver by Liv-52 from the deleterious effects of carbontetrachloride (CC14) by determining the biological half-life of 131I-Rose bengal in male albino rats. An increase in the biological half-life of the radio-iodinated dye was observed following CC14 intoxication which was reversed by Liv-52 treatment.

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