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Figure 1: Schema of the cleaned-up KBP modeling methods. The KBPC-DVHmodel was created by excluding cases that did not meet the clinical goal based on DVH plots. The KBPC-REGmodel was created by excluding cases outside ±1 standard deviation from PCA regression plots. Finally, the KBPC-ALLmodel was created by excluding all cleaned-up cases as in both the KBPC-DVHand KBPC-REGmodels. KBP: Knowledge-based treatment planning, DVH: Dose–volume histogram, PCA: Principal component analysis

Figure 1: Schema of the cleaned-up KBP modeling methods. The KBP<sub>C-DVH</sub>model was created by excluding cases that did not meet the clinical goal based on DVH plots. The KBP<sub>C-REG</sub>model was created by excluding cases outside ±1 standard deviation from PCA regression plots. Finally, the KBP<sub>C-ALL</sub>model was created by excluding all cleaned-up cases as in both the KBP<sub>C-DVH</sub>and KBP<sub>C-REG</sub>models. KBP: Knowledge-based treatment planning, DVH: Dose–volume histogram, PCA: Principal component analysis