Journal of Medical Physics
ORIGINAL ARTICLE
Year
: 2020  |  Volume : 45  |  Issue : 1  |  Page : 7--15

Dosimetric Comparison of treatment plans computed with finite size pencil beam and monte carlo algorithms using the incise™ multileaf collimator-equipped cyberknife® system


Kalpani Nisansala Udeni Galpayage Dona1, Charles Shang2, Theodora Leventouri1 
1 Department of Physics, Florida Atlantic University, Boca Raton, Florida, USA
2 Department of Physics, Florida Atlantic University, Boca Raton; South Florida Proton Therapy Institute, Delray Beach, Florida, USA

Correspondence Address:
Ms. Kalpani Nisansala Udeni Galpayage Dona
Department of Physics, Florida Atlantic University, 777 Glades Road, Boca Raton, Florida
USA

Purpose: InCise™ multileaf collimator (MLC) was introduced for CyberKnife® (CK) Robotic Radiosurgery System (CK-MLC) in 2015, and finite size pencil beam (FSPB) was the only available dose computation algorithm for treatment plans of CK-MLC system. The more advanced Monte Carlo (MC) dose calculation algorithm of lnCise™ was initially released in 2017 for the CK Precision™ treatment planning system (TPS) (v1.1) with new graphic processing unit (GPU) platform. GPU based TPS of the CK offers more accurate, faster treatment planning time and intuitive user interface with smart three-dimensional editing tools and fully automated autosegmentation tools. The MC algorithm used in CK TPS simulates the energy deposited by each individual photon and secondary particles to calculate more accurate dose. In the present study, the dose disparities between MC and FSPB algorithms for selected Stereotactic Ablative Radiation Therapy (SABR) CK-MLC treatment plans are quantified. Materials and Methods: A total of 80 CK-MLC SABR plans computed with FSPB were retrospectively reviewed and compared with MC computed results, including plans for detached lung cancer (or tumors fully surrounded by lung tissues, n = 21), nondetached lung cancer (or tumor touched the chest wall or mediastinum, n = 23), intracranial (n = 21), and pancreas lesions (n = 15). Dosimetric parameters of each planning target volume and major organs at risk (OAR) are compared in terms of normalized percentage deviations (Ndev). Results: This study revealed an average of 24.4% overestimated D95values in plans using FSPB over MC for detached lung (n = 21) and 14.9% for nondetached lung (n = 23) lesions. No significant dose differences are found in intracranial (0.3%, n = 21) and pancreatic (0.9%, n = 15) cases. Furthermore, no significant differences were found in Ndevof OARs. Conclusion: In this study, it was found that FSPB overestimates dose to inhomogeneous treatment sites. This indicates, the employment of MC algorithm in CK-MLC-based lung SABR treatment plans is strongly suggested.


How to cite this article:
Galpayage Dona KN, Shang C, Leventouri T. Dosimetric Comparison of treatment plans computed with finite size pencil beam and monte carlo algorithms using the incise™ multileaf collimator-equipped cyberknife® system.J Med Phys 2020;45:7-15


How to cite this URL:
Galpayage Dona KN, Shang C, Leventouri T. Dosimetric Comparison of treatment plans computed with finite size pencil beam and monte carlo algorithms using the incise™ multileaf collimator-equipped cyberknife® system. J Med Phys [serial online] 2020 [cited 2020 Jul 12 ];45:7-15
Available from: http://www.jmp.org.in/article.asp?issn=0971-6203;year=2020;volume=45;issue=1;spage=7;epage=15;aulast=Galpayage;type=0