Journal of Medical Physics
 Home | Search | Ahead of print | Current Issue | Archives | Instructions | Subscription | Login  The official journal of Association of Medical Physicists of India      
 Users online: 410  Home  EMail this page Print this page Decrease font size Default font size Increase font size 
Year : 2017  |  Volume : 42  |  Issue : 3  |  Page : 123-127

Cardiac dose reduction with deep-inspiratory breath hold technique of radiotherapy for left-sided breast cancer

1 Department of Radiation Oncology, Action Cancer Hospital, New Delhi, India
2 Department of Radiation Oncology, Krishna Institute of Medical Sciences, Hyderabad, Telangana, India

Correspondence Address:
Lalitha Kameshwari Sripathi
Department of Radiation Oncology, Action Cancer Hospital, New Delhi - 110 063
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jmp.JMP_139_16

Rights and Permissions

Introduction: Different techniques of radiation therapy have been studied to reduce the cardiac dose in left breast cancer. Aim: In this prospective dosimetric study, the doses to heart as well as other organs at risk (OAR) were compared between free-breathing (FB) and deep inspiratory breath hold (DIBH) techniques in intensity modulated radiotherapy (IMRT) and opposed-tangent three-dimensional radiotherapy (3DCRT) plans. Materials and Methods: Fifteen patients with left-sided breast cancer underwent computed tomography simulation and images were obtained in both FB and DIBH. Radiotherapy plans were generated with 3DCRT and IMRT techniques in FB and DIBH images in each patient. Target coverage, conformity index, homogeneity index , and mean dose to heart (Heart Dmean), left lung, left anterior descending artery (LAD) and right breast were compared between the four plans using the Wilcoxon signed rank test. Results: Target coverage was adequate with both 3DCRT and IMRT plans, but IMRT plans showed better conformity and homogeneity. A statistically significant dose reduction of all OARs was found with DIBH. 3DCRTDIBHdecreased the Heart Dmeanby 53.5% (7.1 vs. 3.3 Gy) and mean dose to LAD by 28% compared to 3DCRTFB. IMRT further lowered mean LAD dose by 18%. Heart Dmeanwas lower with 3DCRTDIBHover IMRTDIBH (3.3 vs. 10.2 Gy). Mean dose to the contralateral breast was also lower with 3DCRT over IMRT (0.32 vs. 3.35 Gy). Mean dose and the V20of ipsilateral lung were lower with 3DCRTDIBHover IMRTDIBH (13.78 vs. 18.9 Gy) and (25.16 vs. 32.95%), respectively. Conclusions: 3DCRTDIBHprovided excellent dosimetric results in patients with left-sided breast cancer without the need for IMRT.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded164    
    Comments [Add]    

Recommend this journal