Journal of Medical Physics
 Home | Search | Ahead of print | Current Issue | Archives | Instructions | Subscription | Login  The official journal of Association of Medical Physicists of India      
 Users online: 342  Home  EMail this page Print this page Decrease font size Default font size Increase font size 
ORIGINAL ARTICLE
Year : 2007  |  Volume : 32  |  Issue : 3  |  Page : 118-123

Initial experience with an 11 MeV self-shielded medical cyclotron on operation and radiation safety


Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
G S Pant
Department of Nuclear Medicine, AIIMS, New Delhi - 110 029
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0971-6203.35724

Rights and Permissions

A self-shielded medical cyclotron (11 MeV) was commissioned at our center, to produce positron emitters, namely, 18 F, 15 O, 13 N and 11 C for positron emission tomography (PET) imaging. Presently the cyclotron has been exclusively used for the production of 18 F - for 18 F-FDG imaging. The operational parameters which influence the yield of 18 F - production were monitored. The radiation levels in the cyclotron and radiochemistry laboratory were also monitored to assess the radiation safety status in the facility. The target material, 18 O water, is bombarded with proton beam from the cyclotron to produce 18 F - ion that is used for the synthesis of 18 F-FDG. The operational parameters which influence the yield of 18 F - were observed during 292 production runs out of a total of more than 400 runs. The radiation dose levels were also measured in the facility at various locations during cyclotron production runs and in the radiochemistry laboratory during 18 F-FDG syntheses. It was observed that rinsing the target after delivery increased the number of production runs in a given target, as well as resulted in a better correlation between the duration of bombardment and the end of bombardment 18 F - activity with absolutely clean target after being rebuilt. The radiation levels in the cyclotron and radiochemistry laboratory were observed to be well within prescribed limits with safe work practice.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed9986    
    Printed271    
    Emailed14    
    PDF Downloaded628    
    Comments [Add]    
    Cited by others 5    

Recommend this journal