Source of Support: None, Conflict of Interest: None
Patients of state IIB, IIIA and IIIB having exophytic growth and high hypoxic content do not respond well to conventional five fractions a week (5 F/w) radiation treatment. Two fractions a day (10 F/week) radiation with an interval of five hours in between was tried in such cases with a radiobiological basis that normal tissue recovers in 3-4 hours, while malignant tissue takes 6-8 hours to recover. Local control in the form of complete regression of visible disease was such more (84%) in the trial group (2 F/day) in comparison to only 56% in control group (5 F/w). This facilitated intracavitary brachytherapy in larger number of patients. Present study is of three years duration consisting of fifty patients each in trial and control group.